Our Lady of Prompt Succor School was founded in 1952. The school ​started as a 5 classroom school and modern church with a capacity of 400. The growth of the parish was rapid. From the first school numbering 126 pupils, to an evolving elementary school in 1963, with 1,340 pupils and 27 classrooms. 

In 1997, the school was recognized as a National Blue Ribbon School of Excellence, under the direction of the principal, Mrs. Evelyn M. Kingston. She presided over 700 students and almost  60 faculty and staff members until 2005 when Hurricane Katrina devasted St. Bernard Parish. 

Through Ms. Sharon Coll and her faculty and staff, Our Lady of Prompt Succor School once again became the only Catholic school in St. Bernard Parish. She oversaw the rebuilding process, which included the modernization of the Early Learning Center and the building of the state-of-the-art Middle School. She also welcomed the students, parents, and alumni of the former St. Louise, St. Robert, and St. Mark schools. 

Upon Ms. Coll's retirement in 2016, Mrs. Annette Accomando became the third lay principal of Our Lady of Prompt Succor School. Upon her resignation in 2020, Mrs. Charol Armand, a long-time teacher, and Assistant Principal, was named Principal. Through the efforts of her predecessors, the school now boasts an enrollment of 520 students in grades pre-kindergarten three through seventh. Our Lady of Prompt Succor School is nationally accredited through Cognia, formerly AdvancED and SACS. Integrating technology into the curriculum continues with each first through seventh-grade student having an electronic notebook. The school continues to draw students from all St. Bernard Parish, as well as the metro area.